Interferon-gamma release assay for the diagnosis of latent tuberculosis infection: A latent-class analysis
نویسندگان
چکیده
منابع مشابه
Interferon-gamma release assay for the diagnosis of latent tuberculosis infection: A latent-class analysis
BACKGROUND Accurate diagnosis and subsequent treatment of latent tuberculosis infection (LTBI) is essential for TB elimination. However, the absence of a gold standard test for diagnosing LTBI makes assessment of the true prevalence of LTBI and the accuracy of diagnostic tests challenging. Bayesian latent class models can be used to make inferences about disease prevalence and the sensitivity a...
متن کاملUsefulness of interferon-γ release assay for the diagnosis of latent tuberculosis infection in young children
PURPOSE Latent tuberculosis infection (LTBI) in young children may progress to severe active tuberculosis (TB) disease and serve as a reservoir for future transmission of TB disease. There are limited data on interferon-γ release assay (IGRA) performance in young children, which our research aims to address by investigating the usefulness of IGRA for the diagnosis of LTBI. METHODS We performe...
متن کاملInterferon-gamma release assays for the diagnosis of latent tuberculosis infection: an updated review.
Interferon-gamma (IFN-γ) release assays (IGRAs) are in vitro immune tests that have recently been introduced as an alternative to the tuberculin skin test (TST). An increasing body of evidence supports the use of IGRAs for the diagnosis of latent tuberculosis infection (LTBI) in various clinical situations. Currently, two commercial IGRAs are available: the QuantiFERON-TB Gold In-Tube test (QFT...
متن کاملPerformance of an interferon-gamma release assay to diagnose latent tuberculosis infection during pregnancy.
OBJECTIVE To evaluate an interferon (IFN)-gamma release assay in diagnosing latent tuberculosis infection in pregnant adolescents and women at risk for exposure to Mycobacterium tuberculosis. METHODS This was a prospective study of women and adolescents receiving health care at Bellevue Hospital Outpatient Clinics in New York City. Each patient was assessed for M tuberculosis risk factors, ha...
متن کاملDiagnosis of latent tuberculosis infection among HIV discordant partners using interferon gamma release assays
BACKGROUND There is limited data on the effect of HIV status and CD4 counts on performance of Interferon-g Release assays (IGRAs) for diagnosis of latent tuberculosis infection (LTBI). METHODS A cross sectional study was conducted to assess the prevalence of and risk factors for a positive diagnostic test for LTBI, using tuberculin skin test (TST) and IGRAs among HIV-discordant couples in Zam...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0188631